6-Chloro-2-methyl-2H-indazol-5-amine CAS 1893125-36-4 Purity >98.0% (LCMS) Ensitrelvir (S-217622) Intermediate COVID-19
Commercial Supply Ensitrelvir (S-217622) Intermediates:
S-Ethylisothiourea Hydrobromide CAS 1071-37-0
2,4,5-Trifluorobenzyl Bromide CAS 157911-56-3
Trimethyloxonium Tetrafluoroborate CAS 420-37-1
6-Chloro-2-methyl-2H-indazol-5-amine CAS 1893125-36-4
3-(Chloromethyl)-1-methyl-1H-1,2,4-triazole hydrochloride CAS 135206-76-7
1,3,5-Triazine-2,4(1H,3H)-dione, 3-(1,1-dimethylethyl)-6-(ethylthio)- CAS 1360105-53-8
Chemical Name | 6-Chloro-2-methyl-2H-indazol-5-amine |
CAS Number | 1893125-36-4 |
CAT Number | RF-PI1506 |
Stock Status | In Stock |
Molecular Formula | C8H8ClN3 |
Molecular Weight | 181.62 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | Light Brown to Gray Solid Powder |
Purity / Analysis Method | >98.0% (LCMS) |
1 H NMR Spectrum | Consistent With Structure |
LCMS | Consistent With Structure |
Loss on Drying | ≤1.00% |
Total Impurities | <2.00% |
Test Standard | Enterprise Standard |
Usage | Intermediate of Ensitrelvir (S-217622), COVID-19 |
Package: Bottle, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
6-Chloro-2-methyl-2H-indazol-5-amine (CAS: 1893125-36-4) is an intermediate of Ensitrelvir (S-217622). Ensitrelvir by Shionogi & Co. is a highly effective antiviral drug that works just as well as Pfizer's Paxlovid. Oral Xocova (Ensitrelvir), which has the same mechanism of action as Pfizer’s Paxlovid (Nirmatrelvir+Ritonavir), differs in that it only needs to be taken once a day, while the therapeutic effectiveness of ensitrelvir does not seem to be inferior to Paxlovid. As a reminder, Nirmatrelvir is administered twice daily, together with the booster represented by Ritonavir. Ensitrelvir became the first Japanese domestic pill to treat COVID-19, third to be regulatorally approved in Japan; in February 2022.