Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate CAS 178306-47-3 Purity ≥99.0% Factory

Short Description:

Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate 

CAS: 178306-47-3

Appearance: White Powder

Purity: ≥99.0%

Intermediate of API (CAS: 177036-94-1) in the treatment of Pulmonary Arterial Hypertension (PAH)

Inquiry: alvin@ruifuchem.com


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Description:

Chemical Properties:

Chemical Name Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate 
Synonyms 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid Methyl Ester
CAS Number 178306-47-3
CAT Number RF-PI160
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C17H18O4
Molecular Weight 286.32
Density 1.176
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White Powder
Identification IR
Loss On Drying ≤1.00%
Residue on Ignition ≤0.10%
Chromatographic Purity
Single Impurity ≤0.50%
Total Impurities ≤1.00%
Purity ≥99.0% 
Heavy Metals ≤20ppm
Test Standard Enterprise Standard
Usage Intermediate of API (CAS: 177036-94-1)

Package & Storage:

Package: Fluorinated Bottle, Aluminum foil bag, 25kg/Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture

Advantages:

1

FAQ:

Application:

Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate (CAS: 178306-47-3), Intermediate of API (CAS: 177036-94-1). (CAS: 177036-94-1) is a selective endothelin-A (ETA) receptor antagonist introduced for the oral treatment of patients with pulmonary arterial hypertension (PAH), to improve exercise capacity and delay clinical worsening. PAH is a rare disease of the small pulmonary arteries characterized by vascular proliferation and remodeling, resulting in a progressive increase in pulmonary vascular resistance and pulmonary arterial pressure, and ultimately, right ventricular failure and premature death. Early symptoms of PAH include gradual onset of shortness of breath, fatigue, palpitation, edema, and fainting.  

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