Terbinafine Hydrochloride CAS 78628-80-5 Purity >99.0% (T) (HPLC)

Short Description:

Chemical Name: Terbinafine Hydrochloride 

CAS: 78628-80-5

Purity: >99.0% (T) (HPLC)

Appearance: White or Similar White Powder 

API High Quality, Commercial Production

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E-Mail: alvin@ruifuchem.com


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Description:

Leading Manufacturer and Supplier
Intermediates of Terbinafine Hydrochloride
Terbinafine Hydrochloride CAS 78628-80-5
N-Methyl-1-Naphthylmethylamine CAS 14489-75-9
3,3-Dimethyl-1-Butyne CAS 917-92-0
trans-1,3-Dichloropropene CAS 10061-02-6
Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name Terbinafine Hydrochloride  
Synonyms Terbinafine HCl; trans-N-(6,6-Dimethyl-2-Hepten-4-ynyl)-N-Methyl-1-Naphthylmethylamine Hydrochloride; (E)-N,6,6-Trimethyl-N-(Naphthalen-1-ylmethyl)hept-2-en-4-yn-1-Amine Hydrochloride 
CAS Number 78628-80-5 
CAT Number RF2719
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C21H25N·HCl  
Molecular Weight 327.90  
Melting Point 204.0~208.0℃
Sensitive Hygroscopic. Light Sensitive, Air Sensitive, Heat Sensitive
Water Solubility  Slightly Soluble in Water
Solubility in Water Soluble in Anhydrous Ethanol and Methanol, Almost Transparency
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White or Similar White Powder
Identification Infrared Absorption Spectrophotometry. Comparison: Terbinafine Hydrochloride CRS
It Gives Reaction of Chlorides Using Anhydrous Ethanol R as Solvent
Purity / Analysis Method >99.0% (Nonaqueous Titration) 
Purity / Analysis Method >99.0% (HPLC) 
Melting Point 204.0~208.0℃
Loss on Drying <0.50%
Residue on Ignition <0.20%
Heavy Metals <20ppm
Single Impurity <0.20%
Total Impurities <0.50%
pH  3.0~4.5
Residual Solvents
Ethy Acetate <0.50%
Dichloromethan <0.06%
Isopropanol <0.50%
Infrared Spectrum Conforms to Structure
Test Standard Enterprise Standard

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

Terbinafine Hydrochloride (CAS: 78628-80-5) is an oral antifungal agent for the treatment of Trichophyton (Red Trichophyton, Trichophyton rubrum, Trichophyton rubrum, Trichophyton rubrum and Trichophyton rubrum) Infection of skin, hair and nails caused by Microsporum canis and Fusarium oxysporum. It can also treat various rickets (body lice, tinea, hand, foot and head lice, etc.) as well as skin yeast infections caused by Candida (Candida albicans, etc.), and hyperthyroidism caused by mold (for fungal infections). 1. Terbinafine is mainly effective on the dermatophyte group of fungi. 2. As a 1% cream or powder, it is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream works in about half the time required by other antifungals. 3. Oral 250-mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests. Alternatives to oral administration have been studied. 4. Terbinafine may induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy. Terbinafine Hydrochloride entered the the first batch of country announced OTC directory in 2000. This product belongs to antifungal drugs. It has strong effect on shallow fungal infection, and can cure most of the fungal skin diseases through external use.

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